Botox vs. Jeuveau: Understanding Your Options

In the world of cosmetic treatments, neuromodulators like Botox and Jeuveau have gained significant attention for their ability to smooth out fine lines and wrinkles. They’ve become synonymous with anti-aging, rejuvenation, and maintaining a youthful appearance. But how do they differ? And which one is right for you? 

At Circles of Wellness in St. Augustine, FL, we’re here to guide you through the maze of cosmetic injectables. As a destination that offers a wide array of medical spa, day spa, and salon services, we’re committed to helping you make informed decisions about your skincare.

What are Neurotoxins?

At the heart of both Botox and Jeuveau is a substance called botulinum toxin type A. Despite its intimidating name, this compound, when used in small, FDA-approved doses, has a variety of medical and cosmetic uses. Botulinum toxin type A is a neuromodulator, which means it works by temporarily interrupting the signals your nerves send to your muscles. 

In cosmetic use, this interruption in nerve signaling helps relax the facial muscles that contribute to facial wrinkles and fine lines, particularly those that form from repetitive facial expressions such as frowning or squinting. These include the infamous crow’s feet around the eyes and glabellar lines, or frown lines, between the eyebrows. By relaxing these specific muscles, injectable treatments like Jeuveau and Botox allow the skin to smooth out, reducing the appearance of these lines and giving you a fresher, more rested look.

But that’s not all. Neuromodulators have other FDA-approved uses as well. They’re used in treatments for medical conditions like migraines and excessive sweating, or hyperhidrosis. This demonstrates the versatility of these powerful proteins. 

Delving into Botox Cosmetic: The Tried and True Neurotoxin

Botox Cosmetic, also known as onabotulinumtoxinA, is undoubtedly the most well-known neuromodulator. Developed by Allergan, it was the first botulinum toxin type A formulation to be FDA-approved for cosmetic use and gained its initial approval for the treatment of glabellar lines in 2002. Its longstanding presence in the cosmetic world has given it a strong track record, and it’s often the first treatment people think of when it comes to injectable anti-aging solutions.

Botox injections work by blocking nerve signals in the muscles where it is injected, preventing muscle contraction and causing wrinkles to relax and soften. It’s widely used to treat forehead lines, crow’s feet (lines around the eye), and frown lines. 

Beyond cosmetic purposes, Botox has also been approved for a variety of medical conditions, including chronic migraines, excessive underarm sweating (hyperhidrosis), and certain eye muscle conditions.

Introducing Jeuveau – AKA “Newtox”

While Botox might be the household name, a newer player, Jeuveau, has been making waves in the field of cosmetic injectables. Jeuveau was developed by Evolus, a California-based pharmaceutical company, and specifically designed for aesthetic use. Approved by the FDA in 2019 for the treatment of moderate to severe glabellar lines, Jeuveau is the latest neurotoxin to hit the market.

Like Botox, Jeuveau uses botulinum toxin type A to temporarily paralyze muscles, smoothing out the appearance of lines and wrinkles. However, despite having the same active ingredient, Jeuveau has a different formulation process than Botox. While it’s still too early to definitively say how this impacts the results, some patients report noticing a quicker onset of effects with Jeuveau injections.

Jeuveau vs Botox: A Side-by-Side Comparison

When it comes to the showdown of Jeuveau vs Botox, one isn’t necessarily better than the other. Instead, the right choice depends on your unique needs, goals, and circumstances. Let’s take a closer look at how these two powerhouse neuromodulators stack up.

Treatment effectiveness and duration

Both Botox and Jeuveau are FDA-approved to treat fine lines and wrinkles by relaxing the underlying muscles. In clinical trials, both have shown similar efficacy and duration. The effects of both treatments typically become visible within a few days, peak at around two weeks, and can last anywhere from three to six months. It’s worth noting that while some patients report feeling that Jeuveau kicks in a bit faster, more research is needed to conclusively confirm this.

Treatment experience

The experience of getting Botox or Jeuveau injections is essentially the same. Most people describe the injections as feeling like a quick pinch. A numbing cream can be applied before the procedure to enhance your comfort.

Side effects

The side effects for both Botox and Jeuveau are also similar. The most common include mild swelling, redness, or bruising at the injection site, all of which typically resolve quickly. 

Both Jeuveau and Botox are FDA-approved treatments that have been shown to be safe and effective when administered by a qualified professional. As with any cosmetic procedure, it’s crucial to have these treatments performed by a licensed injector, board-certified dermatologist or plastic surgeon to minimize the risk of complications.


The cost for both treatments can vary based on geographic location, the expertise of your injector, and the number of units required to achieve your desired results. As a newer product, Jeuveau was initially introduced at a lower price point to compete with Botox, but the costs are comparable in most practices.

Combining with Other Treatments

Both Botox and Jeuveau can be safely combined with most other cosmetic treatments. Many people choose to pair their neuromodulator injections with other wrinkle treatments such as dermal fillers like Revanesse, RF microneedling, or chemical peels for a more comprehensive approach to facial rejuvenation. Discuss your goals with your provider to develop a treatment plan that meets your needs.

Of course, let’s dive a little deeper into these treatments’ versatility, as both Botox and Jeuveau have numerous applications beyond just cosmetic use.

Beyond Wrinkles: Other Applications of Botox and Jeuveau

While both Jeuveau and Botox are popularly known for their cosmetic uses—specifically, the reduction of fine lines and wrinkles—they also have a range of other applications, showcasing the versatility of these neuromodulators. 

Migraine Relief

Botox, in particular, has received FDA approval for the treatment of chronic migraines. Patients suffering from this condition have found significant relief through regular Botox treatments, with injections typically administered every three months. 

Excessive Sweating

Both Botox and Jeuveau can be used off-label to treat hyperhidrosis, a condition characterized by excessive sweating. This application works by blocking the signals from the nerves that stimulate the sweat glands. The most common treatment areas are the underarms, palms, and soles of the feet.

Eye Conditions

Botox has also been used to treat certain eye conditions such as strabismus (crossed eyes) and blepharospasm (uncontrollable blinking or spasm of the eyelids). It works by relaxing the muscles responsible for these conditions, providing relief to the patients.

Facial Muscle Spasms

Both Botox and Jeuveau have shown efficacy in managing facial spasms. They work by blocking the nerve signals responsible for the muscular activity, thereby helping to reduce the frequency and intensity of spasms.

While Botox has more FDA-approved medical uses due to its longer track record, Jeuveau shows promising potential and is currently undergoing further studies to expand its approved uses. 

Wrapping It Up: Which Is Right For You?

Choosing between Botox and Jeuveau ultimately comes down to your personal preference and the advice of your dermatologist or cosmetic injector. Both offer a safe and effective way to reduce the appearance of wrinkles and fine lines, and each has its loyal fans. Whether you’re considering neuromodulator injections for the first time or you’re thinking about switching between brands, Circles of Wellness in St. Augustine, FL, is here to help guide you on your path to rejuvenation.

Remember, there’s no one-size-fits-all answer when it comes to skin care. The best way to determine which treatment is right for you is through a personalized consultation with our skilled and experienced team. We’re here to answer your questions, discuss your goals, and inform you of any ongoing specials and package deals. Schedule your appointment today!

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